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Clinical Decision Support

Clinical decision support (CDS) systems can enhance the diagnostic process by minimizing diagnostic errors and delays, which are major components of patient safety.


Current CDS efforts are funded by the Agency for Healthcare Research and Quality’sĀ (AHRQ) September 2022 – September 2025

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The goal of CDS for diagnostic imaging is to enhance
evidence-based, effective care delivery.


Assess the technical capabilities of standards used for the exchange of clinical health informationĀ  to represent patient-centered outcomes research (PCOR) guidelines from the HMS-LOE in a higher-level structured representation.


Implementing transparently graded and represented knowledge artifacts will promote widespread dissemination and interoperability across varied HIT platform, end-users and workflows.


Validation and evaluation of the CDS artifacts, including usability and impact on clinical practice, will enhance widespread adoption.

AHRQ Award R18HS028616

Clinical Decision Support for Disseminating and Implementing Patient-Centered Outcomes Research (PCOR) Clinical Evidence

Patient Centered Outcomes Research (PCOR) represents clinical evidence for imaging using national data standards (e.g., Clinical Quality Language) for clinical decision support (CDS), validate the CDS artifacts, and scale them for dissemination and assessment of interoperability in a different institution than that where the CDS artifacts were developed.

Purpose: Disseminate and implement patient-centered outcomes research (PCOR) evidence into clinical practice through clinical decision support (CDS). AHRQ seeks projects that scale interoperable CDS across different health care systems and technologies (e.g., different electronic health records) and that disseminate lessons learned about how to achieve CDS scalability and interoperability.

We will implement CDS for three guidelines using health data standards for interoperability. These include SNOMED-CT, Clinical Quality Language (CQL), and the CDS Hooks application programming interface (API), a specification that builds on the Fast Healthcare Interoperability Resources (FHIR) core specification.


  1. Using breast MRI (instead of or in addition to mammography) for diagnosing a second breast cancer in women previously diagnosed with breast cancer
  2. Using CT scan for diagnosing pulmonary embolism (PE)
  3. Education in a doctor-patient encounter for those at risk for PE
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